H.G. Otten
Laboratory of Translational Immunology
Utrecht
Netherlands
h.g.otten@umcutrecht.nl
Henny Otten is an associate professor with a primary research interest focused on humoral immunity including associated effector mechanisms. He studied medical biology at the University of Amsterdam and obtained his PhD at the Department of Rheumatology of the University Hospital Leiden. In 1992 he started as post-doc at the department of Immunohematology at the University Hospital Utrecht developing molecular HLA-typing and performing research in the field of bone marrow and organ transplantation.
Since 1997 he is co-director of the HLA laboratory in the UMCU. Between 1997-2000 he was also interim head of the bone-marrow transplantation laboratory. He is leader of the national PROCARE consortium which studies the impact of humoral allo- and auto-immunity in approximately 5000 kidney transplants; a study subsidized by Dutch Kidney Foundation. Together with funding from multiple commercial partners, studies are performed on the effector functions of antibodies in relation to complement and FcRgamma polymorphisms, prediction of (the severity of) food allergy and angio-edema, an biomarkers predicting chronic rejection after lung transplantation.
Henny Otten holds certificates as Medical Immunologist, European Specialist in Histocompatibility & Immunogenetics, Transplantation Immunologist, and Immunologist. In close collaboration with clinicians, Henny Otten has (co-)authored over 70 peer-reviewed papers with translational objectives.